Travel options for:
Chicago to Louisville
  • Fly Chicago Midway to Louisville

    $104 - $264
    1. Chicago

      23 min - every 15 minutes

      $3

    2. Chicago Midway (MDW)

      1 h 5 min - non-stop

      $100 - $260

    3. Louisville (SDF)

      28 min - hourly - line 02

      $2

      • Louisville
  • Fly Chicago O'Hare to Louisville

    $99 - $234
    1. Chicago

      43 min - every 10 minutes

      $3

    2. Chicago O'Hare (ORD)

      1 h 8 min - non-stop

      $95 - $230

    3. Louisville (SDF)

      28 min - hourly - line 02

      $2

      • Louisville
  • Fly Chicago O'Hare to Lexington, bus

    $204 - $392
    1. Chicago

      43 min - every 10 minutes

      $3

    2. Chicago O'Hare (ORD)

      1 h 10 min - non-stop

      $150 - $320

    3. Lexington (LEX)

      11 min - 8.2 miles

      $28 - $35

    4. Lexington, KY

      1 h 20 min - 3 times a day

      $24 - $35

      • Louisville
  • Bus Greyhound USA

    $29 - $85
    1. Chicago, IL - Amtrak

      8 h 15 min - 4 times a day

      $29 - $85

      • Louisville, KY
  • Train, bus

    $58 - $104
    1. Chicago Union Station Amtrak

      4 h 54 min - 4 times a week

      $40 - $60

    2. Indianapolis, IN

      3 h 4 min - 4 times a day

      $18 - $45

      • Louisville, KY
  • Bus Amtrak

    $35 - $55
    1. Chicago, IL

      4 h 10 min - once daily

    2. Lafayette, IN

      3 h 55 min - once daily

      $35 - $55

      • Louisville, KY
  • Drive

    $29 - $45
    1. Chicago

      4 h 52 min - 296.7 miles

      $29 - $45

      • Louisville
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From Adams/Wabash subway to Chicago Midway airport, fly to Louisville airport, then line 02 bus to Louisville. 3 h 33 min $214. From Jackson-Blue subway to Chicago O'Hare airport, fly to Louisville airport, then line 02 bus to Louisville. 3 h 56 min $184. From Jackson-Blue subway to Chicago O'Hare airport, fly to Lexington airport, taxi to Lexington, KY, then bus to Louisville. 5 h 24 min $357. From Chicago, IL - Amtrak bus to Louisville, KY. 8 h 15 min $42. From Chicago Union Station Amtrak train to Indianapolis, IN then bus to Louisville, KY. 8 h 58 min $89. From Chicago, IL bus to Lafayette, IN then bus to Louisville, KY. 9 h 5 min $46. From Chicago drive to Louisville. 4 h 52 min $35.